Treatment GuideJuly 11, 2026

Hyperhidrosis Botox: Principles and Effects of Treating Underarm, Hand, and Foot Sweat

By K-DermZip Editorial Team·Based on HIRA public data·Editorial policy
Hyperhidrosis Botox: Principles and Effects of Treating Underarm, Hand, and Foot Sweat

Hyperhidrosis Botox, How Does It Reduce Sweat?

Hyperhidrosis Botox is a treatment used to reduce excessive sweat secretion. It works by temporarily blocking the secretion of acetylcholine, a neurotransmitter that goes to the sweat glands, using botulinum toxin, thereby inhibiting the function of the sweat glands. It can be effectively used for treating localized hyperhidrosis, primarily in areas such as the underarms, hands, and feet.

Principles of Hyperhidrosis Botox Action

Sweat secretion in our body is regulated by the autonomic nervous system. Specifically, the neurotransmitter acetylcholine stimulates the sweat glands (eccrine sweat glands) to secrete sweat. The botulinum toxin used in hyperhidrosis Botox acts to inhibit the secretion of this acetylcholine from nerve endings. As a result, the sweat glands do not receive nerve stimulation, leading to a reduction in sweat production. This effect is temporary, and over time, as the nerve endings recover, sweat secretion function gradually returns.

Which Areas of Hyperhidrosis Can Be Treated?

Hyperhidrosis Botox is primarily effective for localized hyperhidrosis. The most commonly treated areas are as follows:

  • Axillary Hyperhidrosis: Most commonly applied to underarm sweat that causes significant discomfort in daily life, such as wet clothes or odor.
  • Palmar Hyperhidrosis: May be considered when it interferes with activities involving the hands, such as shaking hands, writing, or driving.
  • Plantar Hyperhidrosis: Can be helpful when shoes or socks get wet and cause foot odor.
  • Other Areas: Can also be applied to localized hyperhidrosis in specific areas such as the forehead or scalp, depending on the specialist's judgment.

Hyperhidrosis Botox Procedure and Duration of Effect

The hyperhidrosis Botox procedure is generally relatively simple. The treatment area is disinfected, and anesthetic cream may be applied or ice packs used to reduce pain. Afterward, diluted botulinum toxin is injected in small amounts into multiple points in the areas with excessive sweating. The procedure time varies depending on the area and extent, but usually takes about 10 to 30 minutes.

The effects vary among individuals, but generally begin to appear within 2-3 days after the procedure and reach their maximum effect after 1-2 weeks. The duration of the effect is usually about 4-6 months. If the effect gradually diminishes, re-treatment can be considered, and in some cases, repeated treatments may lead to a slightly longer duration of effect. However, the exact treatment cycle and dosage should be determined in consultation with a specialist.

Precautions for Hyperhidrosis Botox Procedure

Hyperhidrosis Botox is known as a relatively safe procedure, but it is important to be aware of several precautions.

  • Specialist Consultation: Before the procedure, it is essential to consult with a dermatologist to accurately diagnose your type of hyperhidrosis and health condition, and to determine the suitability of Botox treatment.
  • Potential Side Effects: Temporary bruising, swelling, or pain may occur at the injection site. In cases of palmar or plantar treatment, temporary muscle weakness may occur, but it generally recovers within a few weeks. Rarely, allergic reactions may occur, so any unusual symptoms should be reported to the medical staff immediately.
  • Pregnant and Breastfeeding Women: Pregnant or breastfeeding women are advised to avoid Botox procedures.
  • Medications Being Taken: If you are taking medications that may affect blood clotting, such as aspirin, you must inform the medical staff before the procedure.

This article provides general medical information and does not substitute for individual diagnosis or treatment. For accurate information on hyperhidrosis treatment and a personalized treatment plan, please consult with a dermatologist.

Clinics with Registered Related Procedure Information

This is an alphabetical listing and not a ranking or medical recommendation. Procedure information is based on content registered by each clinic. (Source: K-Dermzip)

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K-DermZip is a specialized Korean dermatology platform based on HIRA public data. This content is informational and complies with Korean medical advertising regulations.